This triple analysis focuses on cancer drug development strategies in one specific cancer indication (Melanoma), one mechanism/target/effect area (Cancer Vaccines) and one compound specific area (Antibodies). Each of these three individual parts is evaluated according to standardized criteria in a five pillar pipeline drug assessment methodology to compare drug development strategies in oncology. This makes it easy to find and compare analysis not only within one single cancer focus area but also between different areas.
Below is a short synopsis of each part included in this report:
Part I: Melanoma
The melanoma report part comprises defined and up to date development strategies for 218 melanoma drugs within the portfolio of 138 investigators, from Ceased to Marketed. This part extensively analyses their 170 identified drug targets, organized into 151 drug target strategies, and assesses them in eight different compound strategies in melanoma.
This part is based on the following publication:
A Decision Support Tool for Optimizing the Melanoma Pipeline: From Research and Development to Market
Part II: Cancer Vaccines
The cancer vaccine report part comprises defined and up to date development strategies for 155 cancer vaccine drugs within the portfolio of 99 investigators, from Ceased to Marketed. This part extensively analyses their 94 identified drug targets, organized into 91 drug target strategies, and assesses them in 42 different cancer indications.
This part is based on the following publication:
Commercializing Cancer Vaccines: A Decision Support Tool for Optimizing the Pipeline
Part III: Antibodies
The cancer antibody drug report part comprises defined and up to date development strategies for 531 antibody drugs in oncology within the portfolio of 196 companies world-wide, from Ceased to Marketed. The report extensively analyses their 255 identified drug targets, organized into 266 drug target strategies, and assesses them in 75 cancer indications.
This part is based on the following publication:
The Global Competitive Landscape of Antibody Drug Development in Cancer: The Faster Route to Consider Your Options and Position of Others
The report is written for you to understand and assess the impact of competitor entry and corresponding changes to development strategies for your own portfolio products. It helps teams to maximize molecule value by selecting optimal development plans and manage risk and uncertainty. The report serves as an external commercial advocate for pharmaceutical companies’ pipeline and portfolio planning (PPP) in cancer by:
* Providing you with competitive input to the R&D organization to guide development of early product ideas and ensure efforts are aligned with business objectives
* Assisting you to make informed decisions in selecting cancer indications that are known to be appropriate for your drug’s properties
* Analyzing, correlating and integrating valuable data sources in order to provide accurate data for valuation of pipeline, in-licensing and new business opportunities
* Providing you with commercial analytic support for due diligence on in-licensing and acquisition opportunities
* Supporting development of integrative molecule, pathway and disease area strategies
* Integrating knowledge for you to consider the therapeutic target for the highest therapeutic outcome and return on investment
This report provides systems, analytical and strategic support both internally to PPP and to stakeholders across your own organization. The report will also be an important part of creating and implementing a market development plan for cancer drugs to insure that the optimal market conditions exist by the time the products are commercialized.
Key Topics Covered:
Part I: Melanoma
5.1 The Scope of this Report 25
6 Consider the Therapeutic Target Among Melanoma Drugs for the Highest Therapeutic Outcome and Return on Investment (170 Drug Targets) 29-363
7 Emerging New Products to Established Ones: Drug Target Strategies of Melanoma Drugs by their Highest Stage of Development (151 Drug Target Strategies and 218 Melanoma Drugs) 364-538
8 Compound Strategies at Work: Competitive Benchmarking of Melanoma Drugs by Compound Strategy (8 Compound Strategies) 539-574
9 Pipeline and Portfolio Planning: Competitive Benchmarking of the Melanoma Drug Pipeline by Investigator (138 Companies) 575-766
10 Disclaimer 767
11 Drug Index 768
12 Company Index 773
Figures: Includes 6 Figures
Tables: Includes 196 Tables
Total Number of Pages: 777
Part II: Cancer Vaccines
5.1 The Scope of this Report 26
6 Consider the Therapeutic Target Among Cancer Vaccine Drugs for the Highest Therapeutic Outcome and Return on Investment (94 Drug Targets) 30-194
7 Emerging New Products to Established Ones: Drug Target Strategies of Cancer Vaccine Drugs by their Highest Stage of Development (91 Drug Target Strategies and 155 Cancer Vaccine Drugs) 195-308
8 Compound Strategies at Work: Competitive Benchmarking of Cancer Vaccine Drugs by Compound Strategy (7 Compound Strategies) 309-338
9 Selecting Cancer Indications for Cancer Vaccine Drugs (42 Cancer Indications) 339-386
10 Pipeline and Portfolio Planning: Competitive Benchmarking of the Cancer Vaccine Drug Pipeline by Investigator (99 Investigators) 387-649
11 Disclaimer 650
12 Drug Index 651
13 Company Index 656
Figures: Includes 6 Figures
Tables: Includes 205 Tables
Total Number of Pages: 659
Part III: Antibodies
5.1 The Scope of this Report 35
6 Consider the Therapeutic Target Among Antibody Drugs in Oncology for the Highest Therapeutic Outcome and Return on Investment (255 Drug Targets) 39-430
7 Emerging New Products to Established Ones: Drug Target Strategies of Antibody Drugs in Oncology by their Highest Stage of Development (266 Drug Targets Strategies and 531 Antibody Drugs) 431-768
8 Selecting Cancer Indication for Antibody Drugs (75 Cancer Indications) 769-893
9 Pipeline and Portfolio Planning: Competitive Benchmarking of the Antibody Drug Pipeline in Oncology by Investigator (196 Investigators and 531 Antibody Drugs) 894-1,916
10 Disclaimer 1917
11 Drug Index 1918
12 Company Index 1934
Figures: Includes 5 Figures
Tables: Includes 347 Tables
Total Number of Pages: 1,944
3SBio
A&G Pharmaceutical
Abbott
Abiogen
Ablynx
Abraxis BioScience
AC Immune
Acceleron Pharma
Access
Actelion
Actinium Pharmaceuticals
Active Biotech
Adaptimmune
Adherex
Aduro BioTech
Advanced Life Sciences
Advaxis
AEterna Zentaris
Affibody
Affimed Therapeutics
Affitech
AGY Therapeutics
Aida Pharmaceuticals
Akela Pharma
Alder Biopharmaceuticals
Alethia Biotherapeutics
Alexion
Alfacell
Algeta
Alnylam
AlphaVax
ALSP
Altor BioScience
Ambit Biosciences
Amgen
Amorfix Life Sciences
AngioChem
Antisense Pharma
Antisoma
Aphios
ApopLogic Pharmaceuticals
Apotex
Apricus Biosciences
Apthera
Arana Therapeutics
Arca biopharma
arGEN-X
Ariad
ArQule
Array BioPharma
Astellas
Astex Therapeutics
AstraZeneca
Attenuon
Avaxia
AVEO
AVI BioPharma
Bavarian Nordic
Bayer
Bellicum Pharmaceuticals
Berkeley Lab
Bio-Medisinsk Innovasjon
BioAlliance Pharma
Biocon
Biogen Idec
BioInvent
Biokine Therapeutics
Biolex
BioLineRx
BioNumerik
Biosceptre
Biostar
Biotecnol
Biotest
BioVex
Boehringer Ingelheim
Bristol-Myers Squibb
BTG
Cadila
Cancer Innovations
Cancer Research Technology
CDG Therapeutics
Cell Genesys
Celldex Therapeutics
Celltrion
Celtic Pharma
Center of Molecular Immunology
CG Therapeutics
Circadian Technologies
CJ Corp
Clavis Pharma
Cosmo Pharmaceuticals
CSL
CuraGen
CureTech
CytImmune Sciences
Cytokinetics
Daewoong
Daiichi Sankyo
Dara Biosciences
Deciphera Pharmaceuticals
Dendreon
DeveloGen
DiaMedica
DNAVEC
Dompe
Dong-A
Dr Reddy’s
Dyax
Eisai
Elan
Eli Lilly
Emergent BioSolutions
EntreMed
Enzon
Epeius Biotechnologies
EpiCept
Epitomics
EUSA Pharma
Exelixis
Facet Biotech
Faron Pharmaceuticals
Favrille
Femta Pharmaceuticals
FibroGen
Five Prime Therapeutics
Flamel Technologies
Fusion Antibodies
Galaxy Biotech
GammaCan
Ganymed Pharmaceuticals
Gene Techno Science
Genencor
Genentech
Generex
Genmab
GenOdyssee Pharmaceuticals
Genomic Systems
GenPat77
Genta
GENTICEL
GenVec
Genzyme
Geron
Gilead Sciences
GlaxoSmithKline
Gliknik
GlobeImmune
Glycotope
Gradalis
Green Cross
Hawthorn Pharmaceuticals
Hemispherx Biopharma
Hoffmann-La Roche
Human Genome Sciences
Ichor Medical Systems
Idera Pharmaceuticals
IDM Pharma
ImClone Systems
IMED
Immune Pharmaceuticals
ImmunoCellular Therapeutics
Immunocore
ImmunoFrontier
ImmunoGen
Immunomedics
Immunotope
Immutep
Infinity Pharmaceuticals
Innate Pharma
InNexus Biotechnology
Inotek
Inovio
Intracel
Intrexon
Introgen Therapeutics
Ipsen
ISA Pharmaceuticals
ISU ABXIS
Jennerex Biotherapeutics
Johnson & Johnson
Kaketsuken
KaloBios
Kalypsys
Karyon-CTT
Kiadis
Kirin Pharma
Kissei
Kyowa Hakko Kirin
Kyto Biopharma
LFB Biotechnologies
LG Life Sciences
MacroGenics
Mannkind
MAT Biopharma
Medarex
Medical Marketing International
MediGene
MedImmune
Medisyn Technologies
Menarini
Merck & Co
Merck KGaA
Merrimack
Micromet
Mitsubishi Tanabe Pharma
Mochida
Mojave Therapeutics
MolMed
Mologen
Mycenax
Nemod Biotherapeutics
Neovacs
Neuren
NIH
NKT Therapeutics
Non-industrial source
Northwest Biotherapeutics
Novartis
NovaRx
Novogen
Oncalis
OncoMed
OncoMune
OncoTherapy Science
Oncothyreon
Oncovir
Onyvax
OSI Pharmaceuticals
Oxford BioMedica
Paladin Labs
Panacea
PanGenetics
Patrys
PBL Therapeutics
Pepscan Systems
Pepscan Therapeutics
Peregrine Pharmaceuticals
Perseus Proteomics
Pfizer
PharmaMar
Pharmexa
Philogen
PhiloGene
Pierre Fabre
Piramal
Plexxikon
Prima Biomed
ProCell Therapeutics
Prochon Biotech
Progen
Progenics Pharmaceuticals
Protherics
Radient Pharmaceuticals
Ramot
Reata Pharmaceuticals
Recepta biopharma
Receptor BioLogix
Regeneron
Regulon
responsif
Sanofi-Aventis
Santaris Pharma
Sareum
SBI Biotech
Scancell
SciClone Pharmaceuticals
Seattle Genetics
Shenogen
Shire
Simcere Pharmaceuticals
Solbec Pharmaceuticals
Spirogen
Stainwei Biotech
Sunol Molecular
SuperGen
SuppreMol
Swedish Orphan Biovitrum
Switch Pharma
Symphogen
Synageva BioPharma
SynerGene Therapeutics
Takeda
TapImmune
Targa Therapeutics
Targepeutics
TeGenero
Teva
Thallion Pharmaceuticals
Therapure Biopharma
Therion Biologics
ThromboGenics
Titan Pharmaceuticals
Tolerx
TopoTarget
Tracon Pharmaceuticals
Transgene
Trillium Therapeutics
Trion Pharma
UCB
United Biomedical
United Therapeutics
Vaccinex
Wakunaga
VasGene Therapeutics
Vaxil BioTherapeutics
Vaxon Biotech
VaxOnco
VBL Therapeutics
Vectura
Vical
Wilex
VioQuest
Viragen
Virionics
ViroMed
ViroTarg
Viventia Biotech
XBiotech
Xencor
Xerion
Xoma
Y’s Therapeutics
YM BioSciences
York Pharma
Zenotech
Zensun
ZymoGenetics
131I-tositumomab
abagovomab
ADXS11-001
AE-37
aflibercept
AG-14699
agatolimod
aldesleukin
alemtuzumab
ALT-801
ALVAC-CEA/B7.1
AMG-386
APO-866
astuprotimut-r
AVX-701
axitinib
bardoxolone methyl
belagenpumatucel-L
belinostat
bevacizumab
BMS-663513
bortezomib
bosentan
BP-GMAX-CD1
brentuximab vedotin
Cadi-05
catumaxomab
CB-10-01
CEA-TRICOM
cetuximab
CG-201
CMLVAX-100
cositecan
CTL901
CTP-37
CVac
dasatinib
DCVax-prostate
decitabine
denenicokin
denosumab
dovitinib lactate
E-75
EMD-273063
endostatin
entinostat
epirubicin
everolimus
Exherin
farletuzumab
fowlpox-PSA vaccine
fresolimumab
galiximab
gefitinib
gemtuzumab ozogamicin
girentuximab
glembatumumab
golnerminogene pradenovec
GRNVAC1
GT-111
GV-1001
GV-1002
GVAX
GVX-3322
Her-2/Neu peptides
histamine dihydrochloride
ibritumomab tiuxetan
IGN-101
imatinib mesilate
ImmunoVEX tri-melan
IMO-2055
IMP-321
INGN-225
INGN-241
inotuzumab ozogamicin
interferon-alpha
interferon-alpha2
interferon-alpha2a
interferon-alpha2b
interferon-beta
interleukin-2, 2nd-generation
intetumumab
IPH-1101
ipilimumab
ispinesib mesylate
JX-594
kahalalide F
L19-IL2
LipoVIL12
lumiliximab
MAGE-3-TK
MDX-1106
ME-103
MetXia
MGN-1601
MKC-1106-MT
MSI vaccine
MVA-BN
MVA-BN Her-2 vaccine
naptumomab estafenatox
necitumumab
nimotuzumab
Norelin
obinutuzumab
oblimersen sodium
ofatumumab
OncoVEX GM-CSF
Onyvax-105
oregovomab
OTS-102
P-276-00
panitumumab
PANVAC-VF
pDOM-PSMA27
peginterferon alfa-2b
PEP-223
perifosine
pertuzumab
plitidepsin
PLX-4032
poly-ICLC
PR1:169-177 peptide
PROSTVAC
PX-104.1
ramucirumab
Reditux
retaspimycin
Reximmune-C
rindopepimut
rituximab
sagopilone
SAI-EGF
sargramostim
selumetinib
sodium stibogluconate
Stimuvax
sunitinib malate
TG-4001
TG-4010
thymalfasin
topotecan
trabedersen
trastuzumab
tremelimumab
TroVax
velimogene aliplasmid
veliparib
verpasep caltespen
volociximab
VX-001
YM-155
zalutumumab
zanolimumab
ZYC-300
Other selected research from the 'Triple Analysis' category:
Triple Analysis: Lung Cancer, Angiogenesis and Protein Kinase Inhibitors
Triple Analysis: Breast Cancer, Melanoma and Cancer Vaccines
Other selected research from the 'Oncology' category:
Triple Analysis: Leukemia, Melanoma and Protein Kinase Inhibitors
Strategic Outlook on Protein Kinase Inhibitors in Oncology
