This triple analysis focuses on cancer drug development strategies in one specific cancer indication (Melanoma), one mechanism/target/effect area (Angiogenesis) and one compound specific area (Antibodies). Each of these three individual parts is evaluated according to standardized criteria in a five pillar pipeline drug assessment methodology to compare drug development strategies in oncology. This makes it easy to find and compare analysis not only within one single cancer focus area but also between different areas.
Below is a short synopsis of each part included in this report:
Part I: Melanoma
The melanoma report part comprises defined and up to date development strategies for 218 melanoma drugs within the portfolio of 138 investigators, from Ceased to Marketed. This part extensively analyses their 170 identified drug targets, organized into 151 drug target strategies, and assesses them in eight different compound strategies in melanoma.
This part is based on the following publication:
A Decision Support Tool for Optimizing the Melanoma Pipeline: From Research and Development to Market
Part II: Angiogenesis
The angiogenesis affecting cancer drug report part comprises defined and up to date development strategies for 252 drugs in oncology within the portfolio of 151 companies world-wide, from Ceased to Marketed. The report extensively analyses their 177 identified drug targets, organized into 170 drug target strategies, and assesses them in 70 cancer indications.
This part is based on the following publication:
Commercializing Angiogenesis Affecting Drugs in Cancer: The Faster Route to Consider Your Options and Position of Others
Part III: Antibodies
The cancer antibody drug report part comprises defined and up to date development strategies for 531 antibody drugs in oncology within the portfolio of 196 companies world-wide, from Ceased to Marketed. The report extensively analyses their 255 identified drug targets, organized into 266 drug target strategies, and assesses them in 75 cancer indications.
This part is based on the following publication:
The Global Competitive Landscape of Antibody Drug Development in Cancer: The Faster Route to Consider Your Options and Position of Others
The report is written for you to understand and assess the impact of competitor entry and corresponding changes to development strategies for your own portfolio products. It helps teams to maximize molecule value by selecting optimal development plans and manage risk and uncertainty. The report serves as an external commercial advocate for pharmaceutical companies’ pipeline and portfolio planning (PPP) in cancer by:
* Providing you with competitive input to the R&D organization to guide development of early product ideas and ensure efforts are aligned with business objectives
* Assisting you to make informed decisions in selecting cancer indications that are known to be appropriate for your drug’s properties
* Analyzing, correlating and integrating valuable data sources in order to provide accurate data for valuation of pipeline, in-licensing and new business opportunities
* Providing you with commercial analytic support for due diligence on in-licensing and acquisition opportunities
* Supporting development of integrative molecule, pathway and disease area strategies
* Integrating knowledge for you to consider the therapeutic target for the highest therapeutic outcome and return on investment
This report provides systems, analytical and strategic support both internally to PPP and to stakeholders across your own organization. The report will also be an important part of creating and implementing a market development plan for cancer drugs to insure that the optimal market conditions exist by the time the products are commercialized.
Key Topics Covered:
Part I: Melanoma
5.1 The Scope of this Report 25
6 Consider the Therapeutic Target Among Melanoma Drugs for the Highest Therapeutic Outcome and Return on Investment (170 Drug Targets) 29-363
7 Emerging New Products to Established Ones: Drug Target Strategies of Melanoma Drugs by their Highest Stage of Development (151 Drug Target Strategies and 218 Melanoma Drugs) 364-538
8 Compound Strategies at Work: Competitive Benchmarking of Melanoma Drugs by Compound Strategy (8 Compound Strategies) 539-574
9 Pipeline and Portfolio Planning: Competitive Benchmarking of the Melanoma Drug Pipeline by Investigator (138 Companies) 575-766
10 Disclaimer 767
11 Drug Index 768
12 Company Index 773
Figures: Includes 6 Figures
Tables: Includes 196 Tables
Total Number of Pages: 777
Part II: Angiogenesis
5.1 The Scope of this Report 37
6 Consider the Therapeutic Target Among Angiogenesis Affecting Drugs in Oncology for the Highest Therapeutic Outcome and Return on Investment (177 Drug Targets) 41-421
7 Emerging New Products to Established Ones: Drug Target Strategies of Angiogenesis Affecting Drugs in Oncology by their Highest Stage of Development (170 Drug Target Strategies and 252 Drugs) 424-666
8 Compound Strategies at Work: Competitive Benchmarking of Angiogenesis Affecting Cancer Drugs by Compound Strategy (7 Compound Strategies) 667-709
9 Selecting Indication for Angiogenesis Affecting Drugs in Oncology (70 Cancer Indications) 710-848
10 Pipeline and Portfolio Planning: Competitive Benchmarking of the Angiogenesis Affecting Drug Pipeline in Oncology by Investigator (151 Investigators and 252 Drugs) 849-1685
12 Drug Index 1687
13 Company Index 1697
Figures: Includes 7 Figures
Tables: Includes 310 Tables
Total Number of Pages: 1,704
Part III: Antibodies
5.1 The Scope of this Report 35
6 Consider the Therapeutic Target Among Antibody Drugs in Oncology for the Highest Therapeutic Outcome and Return on Investment (255 Drug Targets) 39-430
7 Emerging New Products to Established Ones: Drug Target Strategies of Antibody Drugs in Oncology by their Highest Stage of Development (266 Drug Targets Strategies and 531 Antibody Drugs) 431-768
8 Selecting Cancer Indication for Antibody Drugs (75 Cancer Indications) 769-893
9 Pipeline and Portfolio Planning: Competitive Benchmarking of the Antibody Drug Pipeline in Oncology by Investigator (196 Investigators and 531 Antibody Drugs) 894-1,916
10 Disclaimer 1917
11 Drug Index 1918
12 Company Index 1934
Figures: Includes 5 Figures
Tables: Includes 347 Tables
Total Number of Pages: 1,944
3SBio
A&G Pharmaceutical
Abbott
Abiogen
Ablynx
Abraxis BioScience
AC Immune
Acceleron Pharma
Access
Actelion
Actinium Pharmaceuticals
Active Biotech
Adherex
Advanced Life Sciences
Advantagene
Advaxis
Advenchen
AEterna Zentaris
Affibody
Affimed Therapeutics
Affitech
Agennix
AGY Therapeutics
Aida Pharmaceuticals
Alder Biopharmaceuticals
Alethia Biotherapeutics
Alexion
Alfacell
Algeta
Alnylam
ALSP
Altor BioScience
Ambit Biosciences
Ambrilia Biopharma
Amgen
Amorfix Life Sciences
Amphora
AngioChem
Angiogen
Angiogenex
Angstrom Pharmaceuticals
Ansaris
Antisense Pharma
Antisoma
Aphios
ApopLogic Pharmaceuticals
Apotex
Apricus Biosciences
Arana Therapeutics
Arca biopharma
arGEN-X
Ariad
Arno Therapeutics
ArQule
Array BioPharma
Astellas
Astex Therapeutics
AstraZeneca
Attenuon
Austrianova
Avaxia
AVEO
Bayer
Berkeley Lab
Bio-Medisinsk Innovasjon
BioAlliance Pharma
BioAxone
Biocad
Biocon
Biogen Idec
BioInvent
Biokine Therapeutics
Biolex
BioLineRx
BioNumerik
Biosceptre
Biotecnol
Biotest
BioVex
Boehringer Ingelheim
Bolder BioTechnology
Bristol-Myers Squibb
BTG
Cancer Innovations
Cancer Research Technology
CDG Therapeutics
Celecure
Celera
Celgene
Cell Genesys
Cell Therapeutics
CellCeutix
Celldex Therapeutics
Cellmid
Celltrion
Celtic Pharma
Center of Molecular Immunology
Cephalon
CG Therapeutics
ChemoCentryx
Chemokine Therapeutics
China Sky One Medical
Choongwae
Circadian Technologies
CJ Corp
Clavis Pharma
Cosmo Pharmaceuticals
CSL
Cue Biotech
CuraGen
CureTech
Curis
Cyclacel
CytImmune Sciences
Cytochroma
Cytokinetics
Daewoong
Daiichi Sankyo
Dara Biosciences
Deciphera Pharmaceuticals
Dendreon
DiaMedica
DNAVEC
Dompe
Dong-A
Dr Reddy’s
Dyax
Eisai
Elan
Eli Lilly
Emergent BioSolutions
EntreMed
Enzon
EpiCept
Epitomics
EUSA Pharma
Exelixis
ExonHit Therapeutics
Facet Biotech
Faron Pharmaceuticals
Favrille
Femta Pharmaceuticals
FibroGen
Five Prime Therapeutics
Flamel Technologies
Fusion Antibodies
Galaxy Biotech
GammaCan
Ganymed Pharmaceuticals
Gene Techno Science
Genencor
Genentech
Genmab
Genomic Systems
GenPat77
Genta
GenVec
Genzyme
Gilead Sciences
GlaxoSmithKline
Gliknik
GlycoGenesys
Glycotope
Green Cross
Hawthorn Pharmaceuticals
Hemispherx Biopharma
Hoffmann-La Roche
Human Genome Sciences
Hy BioPharma
Ichor Medical Systems
Idera Pharmaceuticals
IDM Pharma
ImClone Systems
IMED
Immune Pharmaceuticals
ImmunoCellular Therapeutics
Immunocore
ImmunoGen
Immunomedics
ImmuPharma
Immutep
Infinity Pharmaceuticals
Innate Pharma
InNexus Biotechnology
Inotek
Inovio
Intracel
Intrexon
Introgen Therapeutics
Ipsen
ISA Pharmaceuticals
Isis Pharmaceuticals
ISU ABXIS
Jennerex Biotherapeutics
Johnson & Johnson
KAI Pharmaceuticals
Kaketsuken
KaloBios
Kalypsys
Karus Therapeutics
Karyon-CTT
Kiadis
Kirin Pharma
Kissei
Kringle Pharma
Kyowa Hakko Kirin
Kyto Biopharma
Lee’s Pharmaceutical
LFB Biotechnologies
LG Life Sciences
Lorus Therapeutics
MacroGenics
Mannkind
MAT Biopharma
Medarex
MediGene
MedImmune
Medisyn Technologies
Menarini
Merck & Co
Merck KGaA
Merrimack
Mersana Therapeutics
MethylGene
Micromet
Mitsubishi Tanabe Pharma
Mochida
Mojave Therapeutics
MolMed
Mologen
Morvus Technology
Mycenax
Neovacs
Neuren
NewSouth Innovations
NIH
NKT Therapeutics
Non-industrial source
Northwest Biotherapeutics
Novartis
Novelix
Novogen
Noxxon
Oasmia
Oncalis
OncoMed
Onconova
OncoTherapy Science
Oncothyreon
Onyvax
OSI Pharmaceuticals
Oxford BioMedica
OXiGENE
Paladin Labs
Panacea
PanGenetics
Patrys
PBL Therapeutics
Pepscan Therapeutics
PepTx
Peregrine Pharmaceuticals
Perseus Proteomics
Pfizer
Pharmacopeia
PharmaMar
Pharminox
Philogen
PhiloGene
Pierre Fabre
Piramal
Plexxikon
Prima Biomed
ProCell Therapeutics
Prochon Biotech
Progen
Progenics Pharmaceuticals
Protein Sciences
Protgen
PTC Therapeutics
Ramot
Reata Pharmaceuticals
Recepta biopharma
Receptor BioLogix
Regeneron
Regulon
Rexahn
Rigel
Sanofi
Sanofi-Aventis
Santaris Pharma
Sareum
SBI Biotech
Scancell
SciClone Pharmaceuticals
Seattle Genetics
Semafore Pharmaceuticals
Shenogen
Shionogi
Shire
Simcere Pharmaceuticals
Solbec Pharmaceuticals
Spear Therapeutics
Spirogen
SRI International
Stainwei Biotech
Sunol Molecular
SuperGen
SuppreMol
Swedish Orphan Biovitrum
Switch Pharma
Symphogen
Synageva BioPharma
SynDevRx
SynerGene Therapeutics
Taiho
Takeda
Targa Therapeutics
Targepeutics
Tau Therapeutics
TeGenero
Teva
Thallion Pharmaceuticals
Therapure Biopharma
Therion Biologics
ThromboGenics
Tigris Pharmaceuticals
Titan Pharmaceuticals
Tolerx
ToolGen
TopoTarget
Tracon Pharmaceuticals
Transgene
Trillium Therapeutics
Trion Pharma
UCB
United Therapeutics
Vaccinex
Wakunaga
VasGene Therapeutics
VaxOnco
VBL Therapeutics
Vectura
Vical
Wilex
VioQuest
Viragen
ViroTarg
Viventia Biotech
XBiotech
Xencor
Xerion
Xoma
Y’s Therapeutics
YM BioSciences
York Pharma
Zenotech
ZymoGenetics
131I-tositumomab
A6
abagovomab
ABT-510
aflibercept
AG-14699
agatolimod
aldesleukin
alemtuzumab
ALT-801
AMG-386
Angiozyme
apatinib
APO-866
ARQ-197
astuprotimut-r
atrasentan
axitinib
bardoxolone methyl
belinostat
bevacizumab
BIBF-1120
BMS-663513
BMS-690514
bortezomib
bosentan
brentuximab vedotin
brivanib alaninate
catumaxomab
cediranib
cetuximab
cilengitide
cositecan
dasatinib
decitabine
denenicokin
denosumab
DI-17E6
dovitinib lactate
E-7820
EMD-273063
endostatin
ENMD-2076
entinostat
enzastaurin hydrochloride
epirubicin
everolimus
Exherin
farletuzumab
foretinib
fosbretabulin tromethamine
fresolimumab
galiximab
gefitinib
gemtuzumab ozogamicin
girentuximab
glembatumumab
GliaAtak
golnerminogene pradenovec
GT-111
GV-1001
HBP-347
histamine dihydrochloride
ibritumomab tiuxetan
icrucumab
imatinib mesilate
IMP-321
INGN-241
inotuzumab ozogamicin
interferon-alpha
interferon-alpha2
interferon-alpha2a
interferon-alpha2b
interferon-beta
interleukin-2, 2nd-generation
intetumumab
IPH-1101
ipilimumab
IPP-204106
ispinesib mesylate
JI-101
JX-594
kahalalide F
L19-IL2
lenvatinib
linifanib
LipoVIL12
lumiliximab
LY-2275796
MDX-1106
MetXia
MGCD-265
MGN-1601
midostaurin
MKC-1106-MT
motesanib diphosphate
muparfostat (IV)
naptumomab estafenatox
necitumumab
NGR-TNF
nimotuzumab
obinutuzumab
oblimersen sodium
ofatumumab
ON-01910
OncoVEX GM-CSF
oregovomab
OTS-102
P-276-00
paclitaxel
PancAtak
panitumumab
pazopanib hydrochloride
PCI-27483
pegdinetanib
peginterferon alfa-2b
perifosine
pertuzumab
PF-4856884
plitidepsin
PLX-4032
ponatinib
ProstAtak
PTC-299
RAF-265
ramucirumab
Reditux
regorafenib
retaspimycin
ridaforolimus
rituximab
sagopilone
sargramostim
selumetinib
sirolimus
sodium stibogluconate
sorafenib tosylate
SU-6668
sunitinib malate
talactoferrin alfa
TAS-102
tasquinimod
TB-403
telatinib
Tenarad
thymalfasin
tipifarnib
tivozanib
topotecan
trabedersen
trastuzumab
TRC-105
tremelimumab
vandetanib
velimogene aliplasmid
veliparib
vismodegib
volociximab
XL-184
XL-647
YM-155
zalutumumab
zanolimumab
Other selected research from the 'Triple Analysis' category:
Triple Analysis: Lung Cancer, Lymphoma and Angiogenesis
Triple Analysis: Cancer Vaccines, Antibodies and Peptides
Other selected research from the 'Oncology' category:
T Cell Receptor Signaling Pathway in Oncology Drug Pipeline Update 2012
Commercializing Cancer Vaccines: A Decision Support Tool for Optimizing the Pipeline
