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Triple Analysis: Breast Cancer, Melanoma and Apoptosis

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Published Date Jun 12, 2013
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PDF Fact Sheet View Fact Sheet for the report Triple Analysis: Breast Cancer, Melanoma and Apoptosis in PDF
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Find the Triple Analysis Report in oncology which best suits your needs by selecting any three (3) out of these 14 high impact Cancer Focus Areas.

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$3,450.00

Quick Overview

This triple analysis focuses on cancer drug development strategies in both Breast Cancer and Melanoma and by the mechanism/target/effect of Apoptosis.

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This triple analysis focuses on cancer drug development strategies in both Breast Cancer and Melanoma and by the mechanism/target/effect of Apoptosis. Each of these three individual parts is evaluated according to standardized criteria in a five pillar pipeline drug assessment methodology to compare drug development strategies in oncology. This makes it easy to find and compare analysis not only within one single cancer focus area but also between different areas.

Below is a short synopsis of each part included in this report:

Part I: Breast Cancer
The breast cancer drug report part comprises defined and up to date development strategies for 470 drugs within the portfolio of 247 companies world-wide, from Ceased to Marketed. The report extensively analyses their 234 identified drug targets, organized into 223 drug target strategies, and assesses them in breast cancer drug development.
This part is based on the following publication:
Commercializing Breast Cancer Drugs: The Faster Route to Consider Your Options and Position of Others

Part II: Melanoma
The melanoma drug report part comprises defined and up to date development strategies for 282 drugs within the portfolio of 164 companies world-wide, from Ceased to Marketed. The report extensively analyses their 226 identified drug targets, organized into 187 drug target strategies, and assesses them in melanoma.
This part is based on the following publication:
Melanoma Drug Development Analysis: From First-in-Class to Best-in-Class?

Part III: Apoptosis
The apoptotic cancer drug report part comprises defined and up to date development strategies for 234 drugs in oncology within the portfolio of 158 companies world-wide, from Ceased to Marketed. The report extensively analyses their 181 identified drug targets, organized into 157 drug target strategies, and assesses them in 69 cancer indications.
This part is based on the following publication:
Commercializing Apoptotic Drugs in Cancer: The Faster Route to Consider Your Options and Position of Others

The report is written for you to understand and assess the impact of competitor entry and corresponding changes to development strategies for your own portfolio products. It helps teams to maximize molecule value by selecting optimal development plans and manage risk and uncertainty. The report serves as an external commercial advocate for pharmaceutical companies’ pipeline and portfolio planning (PPP) in cancer by:

* Providing you with competitive input to the R&D organization to guide development of early product ideas and ensure efforts are aligned with business objectives

* Assisting you to make informed decisions in selecting cancer indications that are known to be appropriate for your drug’s properties

* Analyzing, correlating and integrating valuable data sources in order to provide accurate data for valuation of pipeline, in-licensing and new business opportunities

* Providing you with commercial analytic support for due diligence on in-licensing and acquisition opportunities

* Supporting development of integrative molecule, pathway and disease area strategies

* Integrating knowledge for you to consider the therapeutic target for the highest therapeutic outcome and return on investment

This report provides systems, analytical and strategic support both internally to PPP and to stakeholders across your own organization. The report will also be an important part of creating and implementing a market development plan for cancer drugs to insure that the optimal market conditions exist by the time the products are commercialized.

Key Topics Covered:

Part I: Breast Cancer
5.1 The Scope of this Report 32
6 Consider the Therapeutic Target Among Breast Cancer Drugs for the Highest Therapeutic Outcome and Return on Investment (234 Drug Targets) 36-522
7 Emerging New Products to Established Ones: Drug Target Strategies of Breast Cancer Drugs by their Highest Stage of Development (223 Drug Target Strategies and 470 Drugs) 523-797
8 Compound Strategies at Work: Competitive Benchmarking of Breast Cancer Drugs by Compound Strategy (8 Compound Strategies) 798-850
9 Pipeline and Portfolio Planning: Competitive Benchmarking of the Breast Cancer Drug Pipeline by Investigator (247 Investigators and 470 Drugs) 851-1723
10 Disclaimer 1724
Figures: Includes 8 Figures
Tables: Includes 309 Tables
Total Number of Pages: 1,755

Part II: Melanoma
5.1 The Scope of this Report 26
6 Consider the Therapeutic Target Among Melanoma Drugs for the Highest Therapeutic Outcome and Return on Investment (226 Drug Targets) 30-467
7 First-in-Class and Me-too Analysis of Melanoma Drugs (187 Drug Target Strategies and 282 Drugs) 468-677
8 Is First-in-Class the Best-in-Class? 488-678
9 Compound Strategies at Work: Competitive Benchmarking of Melanoma Drugs by Compound Strategy (7 Compound Strategies) 679-710
10 The Competition Through Close Mechanistic Approximation of Melanoma Drugs 711
11 Pipeline and Portfolio Planning: Competitive Benchmarking of the Melanoma Drug Pipeline by Company (164 Companies and 282 Drugs) 716-1165
12 Disclaimer 1166
Figures: Includes 5 Figures
Tables: Includes 222 Tables
Total Number of Pages: 1,181

Part III: Apoptosis
5.1 The Scope of this Report 33
6 Consider the Therapeutic Target Among Apoptotic Drugs in Oncology for the Highest Therapeutic Outcome and Return on Investment (181 Drug Targets) 37-416
7 Emerging New Products to Established Ones: Drug Target Strategies of Apoptotic Drugs in Oncology by their Highest Stage of Development (157 Drug Target Strategies and 234 Drugs) 417-622
8 Compound Strategies at Work: Competitive Benchmarking of Apoptotic Cancer Drugs by Compound Strategy(7 Compound Strategies) 623-660
9 Selecting Indication for Apoptotic Drugs in Oncology (69 Cancer Indications) 661-776
10 Pipeline and Portfolio Planning: Competitive Benchmarking of the Apoptotic Drug Pipeline in Oncology by Investigator (158 Investigators and 234 Drugs) 777-1601
Disclaimer 1602
11 Drug Index 1603
12 Company Index 1611
Figures: Includes 7 Figures
Tables: Includes 315 Tables
Total Number of Pages: 1,617

This Report Includes the Following Companies:
3SBio
A&G Pharmaceutical
AB Science
Abbott
AbbVie
Abiogen
Access
Actelion
Adherex
Advanced Life Sciences
Advanomics
Advaxis
AEgera
AEterna Zentaris
Affibody
Affimed Therapeutics
Agenus
Aida Pharmaceuticals
Aileron Therapeutics
Alchemia
Alethia Biotherapeutics
Allos Therapeutics
Alnis Biosciences
Alnylam
AlphaVax
Alseres Pharmaceuticals
Altor BioScience
Ambit Biosciences
Ambrilia Biopharma
Amgen
Anadys Pharmaceuticals
Anaphore
Anavex Life Sciences
AngioChem
Antisense Pharma
Antisoma
Aphios
Apogenix
ApopLogic Pharmaceuticals
Apotex
Ariad
Arno Therapeutics
ArQule
Array BioPharma
Ascend Therapeutics
Ascenta Therapeutics
Ascepion Pharmaceuticals
Astellas
Astex Pharmaceuticals
Astex Therapeutics
AstraZeneca
Attenuon
AVI BioPharma
Avila Therapeutics
Basilea Pharmaceutica
Bavarian Nordic
Bayer
Beta Pharma
Betagenon
Bio-Medisinsk Innovasjon
BioAlliance Pharma
BioAxone
Biocad
Biogen Idec
BioInvent
Biokine Therapeutics
BioLineRx
BioMarin
Biomas
Bionovo
BioNTech
BioNumerik
BioSante
Biosceptre
Biotech Ltd
Biotecnol
BioVex
Boehringer Ingelheim
Bristol-Myers Squibb
BTG
Callisto Pharmaceuticals
Cancer Research Technology
CDG Therapeutics
Cel-Sci
Celera
Celgene
Cell Therapeutics
Celldex Therapeutics
Celltrion
Celsion
Celtic Pharma
Center of Molecular Immunology
Cephalon
ChemoCentryx
Chemokine Therapeutics
Chiesi
Chlorogen
Chong Kun Dang
Chroma Therapeutics
CJ Corp
Clavis Pharma
Cleveland BioLabs
CombinatoRx
CompleGen
Coronado Biosciences
Cosmo Pharmaceuticals
Critical Outcome Technologies
CSL
CureTech
Curis
Cyclacel
Cylene Pharmaceuticals
Cynvec
CytImmune Sciences
Cytochroma
Cytokinetics
CytRx
Daewoong
Daiichi Sankyo
Dainippon Sumitomo Pharma
Dara Biosciences
Debiopharm
Deciphera Pharmaceuticals
Dendreon
DeveloGen
DNAVEC
Domainex
Dong-A
Dongkook Pharm
Douglas
ECI
Eisai
Elara Pharmaceuticals
Eleos
ElexoPharm
Eli Lilly
Emergent BioSolutions
Endoceutics
Enkam Pharmaceuticals
EntreMed
Enzon
Epeius Biotechnologies
EpiCept
Epizyme
Erimos
Esperance Pharmaceuticals
Etubics
Eucodis
Exelixis
Expression Drug Designs
Flamel Technologies
Formula Pharmaceuticals
Fresenius
Galectin Therapeutics
Galena Biopharma
Genentech
Generex
Genmab
Genta
GenVec
Gerolymatos
Geron
Gilead Sciences
GlaxoSmithKline
GlycoGenesys
Glycotope
GlyTag
Got-a-Gene
GPC Biotech
Gradalis
Green Cross
Harbor BioSciences
Heidelberg Pharma
Hemispherx Biopharma
Hoffmann-La Roche
Hospira
Human Genome Sciences
Ichor Medical Systems
Idera Pharmaceuticals
Immunocore
ImmunoGen
Immunomedics
Immunovaccine
ImmuPharma
Immutep
Incyte Corporation
Inex
Infinity Pharmaceuticals
Innate Pharma
InNexus Biotechnology
Inotek
Inovio
Insmed
Insys Therapeutics
Intarcia Therapeutics
Intas Biopharmaceuticals
Intezyne Technologies
Intracel
Intradigm
Intrexon
Introgen Therapeutics
Ipsen
Isis Pharmaceuticals
ISU ABXIS
Jennerex Biotherapeutics
Jina Pharmaceuticals
Johnson & Johnson
KAEL-GemVax
Kalypsys
Karyon-CTT
Keryx Biopharmaceuticals
Kiadis
Kinex
Kyowa Hakko Kirin
Leo
LG Life Sciences
Ligand
Lipotek
Lorus Therapeutics
MacroGenics
Mannkind
Marillion Pharmaceuticals
Marina Biotech
Meda
Medarex
MediGene
MedImmune
Mediolanum
Medisyn Technologies
Menarini
Merck & Co
Merck KGaA
Merrimack
MetaMol Theranostics
MethylGene
Mitsubishi Tanabe Pharma
Mochida
Mojave Therapeutics
MolMed
Mologen
Nektar Therapeutics
Nemod Biotherapeutics
Nereus Pharmaceuticals
Nerviano Medical Sciences
Neurocrine Biosciences
NexGenix Pharmaceuticals
Nidus Laboratories
NIH
Nimbus Discovery
Nippon Kayaku
Nippon Shinyaku
Non-industrial source
Novacea
NovaLead
Novartis
Novelix
Novogen
Oasmia
Oncalis
OncoGenex Pharmaceuticals
Oncolix
OncoMune
Onconova
Oncothyreon
Oncovir
Oncozyme Pharma
Orion Pharma
OSI Pharmaceuticals
Oxford BioMedica
OXiGENE
Pacific Biotech
Paladin Labs
PanaGin
Pantarhei Bioscience
Patrys
PBL Therapeutics
Peregrine Pharmaceuticals
Pfizer
Pharmacyclics
PharmaGap
PharmaMar
Pharmexa
Pharminox
PheneX
Philogen
PhiloGene
Pierre Fabre
Piramal
Progen
ProMetic Life Sciences
ProStrakan
PTC Therapeutics
QLT
R&R
Radient Pharmaceuticals
Raptor Pharmaceutical
Reata Pharmaceuticals
Receptor BioLogix
Regeneron
Regulon
Reliance Life Sciences
RESprotect
Rexahn
Rigel
Rosetta Genomics
Samyang
Sanofi
Santaris Pharma
Santhera Pharmaceuticals
Sareum
Savient Pharmaceuticals
SBI Biotech
Scancell
Schering-Plough
Seattle Genetics
SEEK
Selvita
Semafore Pharmaceuticals
Senesco Technologies
Shenogen
Shire
Sigma-Tau
Simcere Pharmaceuticals
Sirnaomics
Solbec Pharmaceuticals
Spirogen
SRI International
Sun Pharma Advanced Research
Sunesis
SuperGen
Supratek Pharma
Swedish Orphan Biovitrum
Switch Pharma
SymBio Pharmaceuticals
Symbiotec
Synageva BioPharma
Synta Pharmaceuticals
Taiho
Taiwan Liposome Company
Takeda
Tapestry Pharmaceuticals
TapImmune
Targa Therapeutics
Targepeutics
Tau Therapeutics
Taxolog
Telik
TetraLogic Pharmaceuticals
Teva
Thallion Pharmaceuticals
Therion Biologics
Tigris Pharmaceuticals
to-BBB
Tolerx
TopoTarget
Tracon Pharmaceuticals
Tragara Pharmaceuticals
Transgene
Trion Pharma
UMN Pharma
Vaccinex
ValiRx
Vaxon Biotech
VBL Therapeutics
Vectura
Velacor Therapeutics
Verastem
Vernalis
Vertex Pharmaceuticals
Vical
Wilex
Vion Pharmaceuticals
VioQuest
Viragen
Viralytics
ViroMed
ViroTarg
VM Discovery
WntResearch
Wyeth
Xerion
Xoma
Yakult Honsha
YM BioSciences
York Pharma
Zensun
Zydus Cadila
A Shortlist of Drugs Included are:
131I-tositumomab
177-Lu-AMBA
17ß-hydroxysteroid dehydrogenase-1 inhibitors
2-methoxyestradiol
2aG4-IL-2 fus protein + PS MAb
4-hydroxytamoxifen
5-FU
852A
9-aminocamptothecin
AB-16B5
abiraterone acetate
ABT-510
ACC inhibitor
acolbifene
adecatumumab
aderbasib
Adva-27a
AE-37
AEB071
AEE-788
AEG-35156
AEZS-108
afatinib
aflibercept
AFM-21
AG-1
agatolimod
aglycon protopanaxadiol
aldesleukin
ALT-801
alvespimycin hydrochloride
alvocidib
amatuximab
AME-133
AMG-386
amonafide dihydrochloride
amonafide malate
amrubicin hydrochloride
amuvatinib
anastrozole
androgen receptor antagonist
angiopep+paclitaxel
Angiozyme
annamycin
anti-C35 MAb
anti-HER-2/neu antisense
anti-HER2 MAb
anti-HER2neu scFv
anti-Hsp90-alpha MAbs
anti-PCDGF MAbs
anticancers
antiestrogen
APG-101
APO-866
apricoxib
AR-002
AR-004
AR-7BD-33-11A
ARC-100
ARQ-197
ARQ-621
ARRY-380
ARRY-438162
arzoxifene hydrochloride
AS-101
AS-1402
AS-1411
ASP-08126
astuprotimut-r
atamestane
ATN-224
atrasentan
Auto TAG vaccine
AUY-922
AVE-1642
AVI-4126
avorelin
AVX-701
axitinib
AZD-1480
AZD-4547
AZD-4877
AZD-4992
AZD-8931
BAL-27862
banoxantrone
bardoxolone methyl
becatecarin
belinostat
bevacizumab
BEZ-235
BGT-226
BIW-8556
BMN-673
BMS-599626
BMS-663513
BMS-690514
BMS-753493
BMS-754807
BMS-936558
BN-107
bortezomib
bosutinib
brca2
breast cancer therapy
breast cancer vaccine
BreMel/TNF-alpha
BrevaRex MAb
brivanib alaninate
brivudine
Buparlisib
BZL-101
CAB-051
Cabozantinib
cancer therapy (1)
cancer therapy (2)
canertinib dihydrochloride
canfosfamide hydrochloride
capecitabine
carbetocin
catumaxomab
CB-10-01
CDX-1307
CEA cancer vaccine
cediranib
celecoxib
cenersen
cetuximab
CGX-0682
CH-4986399
CHF-4227
cilengitide
cintredekin besudotox
cixutumumab
clofarabine
CNF-2024
conatumumab
contusugene ladenovec
cositecan
CP-724714
crolibulin
CT-011
CTCE-9908
CTP-37
CUDC-101
custirsen
CVac
CX-4945
CYN-101
D-3263
dabigatran etexilate
dalotuzumab
dasatinib
daunorubicin
decitabine
denenicokin
denileukin diftitox
denosumab
Diflomotecan
dinaciclib
docetaxel (1)
docetaxel (2)
docetaxel (3)
docetaxel (4)
docetaxel (5)
docetaxel MAb
dovitinib lactate
doxifluridine
doxorubicin (1)
doxorubicin (10)
doxorubicin (11)
doxorubicin (2)
doxorubicin (3)
doxorubicin (4)
doxorubicin (5)
doxorubicin (6)
doxorubicin (7)
doxorubicin (8)
doxorubicin (9)
doxorubicin citrate
dulanermin
DXL-702
E-75
E39
E7449
ECI-301
elomotecan
elsamitrucin
EMD-273063
emepepimut-S
endostatin
endoxifen
eniluracil
entinostat
enzastaurin hydrochloride
EP-100
epirubicin
epothilone D
erlotinib
ERR antagonists
ertumaxomab
estetrol
estrogen inhibitors
everolimus
exatecan mesylate
exemestane
Exherin
exisulind
EZH2
F16-IL2
fadrozole
FASN inhibitors
figitumumab
flt-4 kinase inhibitors
formestane (1)
formestane (2)
fosbretabulin tromethamine
fosfluridine tidoxil
FPI-01
fresolimumab
fulvestrant
fusion toxins
Galactomycin-UCLT
galarubicin hydrochloride
ganetespib
ganitumab
gataparsen
GDC-0980
gefitinib
gimatecan
glembatumumab vedotin
GlyB4
golnerminogene pradenovec
golvatinib
goserelin
goserelin acetate ER
GPR40 antagonists
GSK-1059615
GSK-1120212
GSK-2118436
GSK-2130579A
GSK-2302024A
GT-111
GV-1001
GVAX
HAS2 inhibitor
HE-3235
Her-2/Neu peptides
HER2 vaccine
her2/neu antigen
Her2/neu gene therapy
Hi-8 MEL
histamine dihydrochloride
huBrE-3 tiuxetan
HuMax-Her2
HuMax-VEGF
ibritumomab tiuxetan
icotinib hydrochloride
icrucumab
idronoxil
IGF-1 receptor inhibitor
IGN-101
IKKe/TBK1 inhibitor
imatinib mesilate
imetelstat
IMGN-388
immunogene therapy
IMO-2055
IMP-321
Imuteran
INCB-028060
INCB-24360
indisulam
ING-1
ingenol mebutate
INGN-225
INGN-241
inherbins
iniparib
INNO-206
interferon
interferon (ß1a)
interleukin-12
interleukin-2
interleukins
intetumumab
IPH-1101
IPH-3102
ipilimumab
IPP-204106
irinotecan
irinotecan hydrochloride
irosustat
ispinesib mesylate
JMR-132
JX-594
kahalalide F
KW-2170
KX2-391
L19-IL2
labetuzumab
labetuzumab-SN-38
Lambrolizumab
lapatinib ditosylate
lapuleucel-T
larotaxel
lasofoxifene
LEE-011
lenvatinib
leptin antagonists
lestaurtinib
letrozole
leucine-doxorubicin
leuprorelin
LGX818
linifanib
linsitinib
LipoVIL12
litronesib
lonafarnib
lonaprisan
LOR-2040
Lovaxin B
lumiliximab
LY-2157299
MAGH-22
mapatumumab
MDX-1140
MDX-1379
ME-103
MEDI-547
Mesd-based peptides
MetXia
MGN-1601
MGN-1703
milataxel
mitoxantrone
MK-2206
MKC-1
MKC-1106-MT
MLN-8237
MM-111
MM-121
mocetinostat
MORAb-004
motesanib diphosphate
motexafin gadolinium
MP-529
MS-209
MT-110
MUC-1 vaccine
MVA-BN Her-2 vaccine
Nab-docetaxel
navitoclax
neratinib
nilotinib
nimotuzumab
NK-012
NL-0031
nolatrexed dihydrochloride
noscapine
NXD-30001
OB-cadherin antibodies
obinutuzumab
oblimersen sodium
OCM-111
OCM-8054
OCM-8224
OGX-225
OGX-427
olaparib
ON-01910
ON-045270
onartuzumab
Onco-L TCS
Oncohist
oncolytic viruses
OncoVAX
OSI-7904L
osteolytic disease therapy
Osteopontin-c inhibitor


P276-00
paclitaxel (1)
paclitaxel (10)
paclitaxel (11)
paclitaxel (12)
paclitaxel (13)
paclitaxel (14)
paclitaxel (2)
paclitaxel (3)
paclitaxel (4)
paclitaxel (5)
paclitaxel (6)
paclitaxel (7)
paclitaxel (8)
paclitaxel (9)
paclitaxel polyglumex
paclitaxel-DHA
PankoPep
panobinostat
PANVAC-VF
PAT-SC1
patupilone
pazopanib hydrochloride
PBI-1402
PCI-24781
PD-0325901
PD-0332991
peginterferon alfa-2b
pelitinib
pemetrexed disodium
pentamidine isethionate
peptidomimetics
perifosine
pertuzumab
PhG-alpha-1
pimasertib
pixantrone
PKI-179
PKI-587
plitidepsin
poly-ICLC
pralatrexate
Prolanta
Prolanta ER
prostate cancer therapy
PRX-321
PSK-3668
PTC-299
PX-104.1
PX-12
quarfloxacin
quinacrine
R-(-)-gossypol
R-763
radiotherapeutic
RAF-265
raloxifene hydrochloride
ramucirumab
retaspimycin
Reximmune-C
Rexin-G
RG-1507
RG-7321
rhErbB3-f
rhIFN-alpha
ridaforolimus
rinfabate
rintatolimod
romidepsin
RR-310
rubitecan
S1P3 inhibitor
sabarubicin
sagopilone
SAR-566658
saracatinib
sargramostim
SBC-202
Sch-57050
SCIB-1
SEL-24-1
seliciclib
selumetinib
semaxanib
seocalcitol
SERM + toxin
SF-1126
simotaxel
sipuleucel-T
siRNA gp96 therapy
SM3
SN-38 (1)
SN-38 (2)
SNG-163
SNG-8023
SNG-8038
sorafenib tosylate
SPC-2968
SPC-2996
SR-13668
SR-16157
SR-31747
ß-lapachone
STA-9090
steroid sulfatase inhibitor
STP-503
SU-14813
SU-6668
sunitinib malate
survivin-2B
Symadex
talminogene laherparepvec
tamoxifen (1)
tamoxifen (2)
tamoxifen, oral liquid
tanespimycin
tariquidar
TAS-108
tegafur + uracil
telomerase vaccine
temsirolimus
Tenarad
terameprocol
tesetaxel
TG-4010
thalidomide
thiocoraline
thymalfasin
thymectacin
tigapotide triflutate
tigatuzumab
tipifarnib
tivozanib
TL-32711
TLK-58130
TLN-4601
TNF + paclitaxel
TNF-alpha
toremifene citrate
trabedersen
trastuzumab (1)
trastuzumab (2)
trastuzumab (3)
trastuzumab emtansine
trastuzumab-MMAE conjugate
tremelimumab
triapine
triciribine phosphate
trilostane
triptorelin pamoate
TroVax
TRU-016
TS-1
TTL-2019
TTL-3101
UCN-01
V-930
V935
vandetanib
varlitinib
vatalanib
velimogene aliplasmid
veliparib
vemurafenib
verubulin
vinflunine ditartrate
vismodegib
vitespen
VM-206
volasertib
volociximab
vosaroxin
VS-4718
VS-507
VS-5095
VX-001
WX-671
WX-UK1
XL-147
XL-647
XL-765
Y-90-labetuzumab
YM-155
zanolimumab
Zemab
zibotentan
ZYC-300

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Other selected research from the 'Oncology' category:


Triple Analysis: Melanoma, Angiogenesis and Peptides
This triple analysis focuses on cancer drug development strategies in one specific cancer indication (Melanoma), one mechanism/target/effect area (Angiogenesis) and one compound specific area (Peptides). Learn More


Biologicals in Oncology Drug Pipeline Update
BioSeeker Group have identified 1371 companies plus partners who are today developing 2823 biological drugs in 6088 developmental projects in cancer across 801 different targets. In addition, there are 25 suspended drugs and another 1050 drugs where development has been ceased. Learn More